About 1 result found for searched term "CMLD012612 " (0.167 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29546 | CMLD012612 | Eukaryotic Initiation Factor |
| CMLD012612 is an amidino-rocaglate containing a hydroxamate group and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012612 inhibits cell translation and is cytotoxic to NIH/3T3 cells with an IC50 value of 2 nM. CMLD012612 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A) and possesses potent anti-neoplastic activity. | ||
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